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DNA Methylation Age Acceleration Is Not Associated with Age of Onset in Parkinson's Disease

7 Aug 2023

Abstract excerpt

BACKGROUND: Epigenetic clocks using DNA methylation (DNAm) to estimate biological age have become popular tools in the study of neurodegenerative diseases. Notably, several recent reports have shown a strikingly similar inverse relationship between accelerated biological aging, as measured by DNAm, and the age of onset of several neurodegenerative disorders, including Parkinson's disease (PD). Common to all of...

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PMID: 37551021
DOI: 10.1002/mds.29574

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