Article
Genetic Modifiers of Age at Onset for Parkinson's Disease in Asians: A Genome-Wide Association Study.
Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2021
Li Chunyu, Ou Ruwei, Chen Yongping, Gu Xiaojing, Wei Qianqian, Cao Bei, Zhang Lingyu, Hou Yanbing, Liu Kuncheng, Chen Xueping, Song Wei, Zhao Bi, Wu Ying, Li Tao, Dong Xianjun, Shang Huifang
Abstract excerpt
BACKGROUND: Age at onset (AAO) is an essential feature of Parkinson's disease (PD) and can help predict disease progression and mortality. Identification of genetic variants influencing AAO of PD could lead to a better understanding of the disease's biological mechanism and provide clinical guidance. However, genetic determinants for AAO of PD remain mostly unknown, especially in the Asian population. OBJECTIVES:...
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