Article
The genetics of pediatric brain tumors.
Current neurology and neuroscience reports - 1 May 2010
Dubuc Adrian M, Northcott Paul A, Mack Stephen, Witt Hendrik, Pfister Stefan, Taylor Michael D
Abstract excerpt
Brain tumors are the most common childhood solid malignancy and the leading cause of cancer-related death in children. Medulloblastoma, ependymoma, supratentorial primitive neuroectodermal tumors, and pilocytic astrocytoma are the most prevalent types, all of which are clinically, histologically, and genetically heterogeneous. Despite an incomplete molecular understanding of these tumors, we have made significant...
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