Insulin receptor substrate 2 gene Gly1057Asp polymorphism is a risk factor for nonalcoholic fatty liver disease.

doi:10.1093/labmed/lmad066

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Insulin receptor substrate 2 gene Gly1057Asp polymorphism is a risk factor for nonalcoholic fatty liver disease.

Laboratory medicine - 7 Mar 2024

Nouri Shadi, Mahmoudi Touraj, Hojjati Farzaneh, Najafabadi Zeinab Nourmohammadi, Shafiee Radmehr, Sayedsalehi Shiva, Dehghanitafti Atefeh, Ardalani Abbas, Kohansal Kiarash, Rezamand Gholamreza, Asadi Asadollah, Nobakht Hossein, Dabiri Reza, Farahani Hamid, Tabaeian Seidamir Pasha, Zali Mohammad Reza

Abstract excerpt

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD), which is an emerging global chronic liver disease, has a close association with insulin resistance. We aimed to determine whether the Gly1057Asp (rs1805097) polymorphism of the insulin receptor substrate 2 (IRS2) gene is associated with NAFLD. METHODS: Using the polymerase chain reaction-restriction fragment length polymorphism method, 135 patients with...

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PMID: 37481466
DOI: 10.1093/labmed/lmad066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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