Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the G1057D polymorphism in insulin receptor substrate 2 gene with type 2 diabetes mellitus: a meta-analysis.

Journal of diabetes and its complications - 1 Jul 2015

Jiang Fan, Li Suyun, Pan Lulu, Jia Chongqi

Abstract excerpt

OBJECTIVES: The G1057D polymorphism in insulin receptor substrate (IRS)-2 gene is associated with type 2 diabetes mellitus (T2DM) risk, but results in published literatures are controversial. In addition, the effect of obesity as a modifier on this association is also inconsistent. Thus, this meta-analysis was performed to assess the above-mentioned association. METHODS: A comprehensive search was performed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Substitution
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Insulin Receptor Substrate Proteins

Share to Models, Genetic

Share to Obesity

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25959789
DOI: 10.1016/j.jdiacomp.2015.04.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the G1057D polymorphism in insulin receptor substrate 2 gene with type 2 diabetes mellitus: a meta-analysis.PMID 25959789Read ↗

Study on the relationship between G1057D variants of IRS2 gene and obese T2DM in Chinese Han subjects.Semantic proximity Read ↗

The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians.Semantic proximity Read ↗

Associations between two single-nucleotide polymorphisms (rs1801278 and rs2943641) of insulin receptor substrate 1 gene and type 2 diabetes susceptibility: a meta-analysis.Semantic proximity Read ↗

The G1057D polymorphism of insulin receptor substrate-2 associated with gestational diabetes mellitus.Semantic proximity Read ↗

IRS-1 genetic polymorphism (r.2963G>A) in type 2 diabetes mellitus patients associated with insulin resistanceSemantic proximity Read ↗

Relationship between IRS-2G1057D variant and type 2 diabetes mellitus in Han population in Liaoning Province, China.Semantic proximity Read ↗

Single nucleotide polymorphisms (SNPs) that are associated with obesity and type 2 diabetes among Asians: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis.Semantic proximity Read ↗

Associations of insulin receptor and insulin receptor substrates genetic polymorphisms with polycystic ovary syndrome: A systematic review and meta-analysis.Semantic proximity Read ↗

The association between leptin receptor gene polymorphisms and type 2 diabetes mellitus: A systematic review and meta-analysis.Semantic proximity Read ↗

Genetic polymorphism of apolipoprotein A5 gene and susceptibility to type 2 diabetes mellitus: a meta-analysis of 15,137 subjects.Semantic proximity Read ↗

Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.