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The common variant of rs6214 in insulin like growth factor 1 (IGF1) gene: a potential protective factor for non-alcoholic fatty liver disease.

Archives of physiology and biochemistry - 1 Feb 2023

Sabzikarian Mohammad, Mahmoudi Touraj, Tabaeian Seidamir Pasha, Rezamand Gholamreza, Asadi Asadollah, Farahani Hamid, Nobakht Hossein, Dabiri Reza, Mansour-Ghanaei Fariborz, Derakhshan Faramarz, Zali Mohammad Reza

Abstract excerpt

PURPOSE: Regarding the central role of insulin resistance in NAFLD, we explored whether insulin-like growth factor 1 (IGF1) and insulin-like growth factor-binding protein 3 (IGFBP3) gene variants were associated with NAFLD susceptibility. METHODS: IGF1 (rs6214) and IGFBP3 (rs3110697) gene variants were genotyped in 154 cases with biopsy-proven NAFLD and 156 controls using PCR-RFLP method. RESULTS: The IGF1 rs6214...

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PMID: 32654522
DOI: 10.1080/13813455.2020.1791187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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