Article
Association of rs5742612 Polymorphism in the Promoter Region of IGF1 Gene with Nonalcoholic Fatty Liver Disease: A Case-Control Study.
Laboratory medicine - 1 Sept 2022
Nobakht Hossein, Mahmoudi Touraj, Rezamand Gholamreza, Tabaeian Seidamir Pasha, Jeddi Golnaz, Asadi Asadollah, Farahani Hamid, Dabiri Reza, Mansour-Ghanaei Fariborz, Kaboli Seyed Alireza, Derakhshan Faramarz, Zali Mohammad Reza
Abstract excerpt
OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) is an emerging global chronic liver disease encompassing a wide spectrum of disorders ranging from simple steatosis to nonalcoholic steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Considering the strong association between NAFLD and insulin resistance, and the vital role of insulin-like growth factor 1 (IGF1) in IR, we hypothesized that IGF1...
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