Article
The rs2275738 variant of the adiponectin receptor 1 gene is associated with biopsy-proven nonalcoholic fatty liver disease.
Personalized medicine - 1 Jan 2024
Rostami Mitra, Mahmoudi Touraj, Ardalani Abbas, Mashaollahi Amirhesam, Zafarjafarzadeh Nikta, Mahban Aidin, Roshani Kosar Babaeian, Ghasemi Fatemeh, Ourang Zahra, Dehghanitafti Atefeh, Kaboli Helia Sadat, Rezamand Gholamreza, Asadi Asadollah, Dabiri Reza, Nobakht Hossein, Tabaeian Seidamir Pasha, Zali Mohammad Reza
Abstract excerpt
Aim: Nonalcoholic fatty liver disease (NAFLD) is a significant health issue worldwide. This study investigated the effect of the adiponectin receptor 1 gene (ADIPOR1) polymorphism on susceptibility to NAFLD.Methods: Data from 330 participants, including 165 biopsy-proven NAFLD patients and 165 healthy controls, were collected. The PCR-RFLP method was used to detect the genotypes of ADIPOR1 rs2275738 or T-106C...
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