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Article

Association of IRS1 gene Pro512Ala polymorphism with nonalcoholic fatty liver disease.

Archives of endocrinology and metabolism - 1 Jan 2024

Asadi Asadollah, Rostami Mitra, Shafiee Radmehr, Ardalani Abbas, Dehghanitafti Atefeh, Golshadi Zakieh, Kohansal Kiarash, Ghasemi Fatemeh, Najafi Maryam, Mahmoudi Touraj, Rezamand Gholamreza, Dabiri Reza, Nobakht Hossein, Farahani Hamid, Tabaeian Seidamir Pasha

Abstract excerpt

Objective: This study was designed to investigate the possible effect of the insulin receptor substrate 1 (IRS1) gene rs1801276 polymorphism on the risk of nonalcoholic fatty liver disease (NAFLD). Subjects and methods: The rs1801276 polymorphism was investigated in 127 controls and 123 biopsy-proven NAFLD patients using PCR-RFLP. Results: No deviation from Hardy-Weinberg equilibrium was discovered for the...

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Identifiers

PMID: 39420901
DOI: 10.20945/2359-4292-2023-0216
PMCID: PMC11460970

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