Article
INSULIN AND INSULIN RECEPTOR GENE POLYMORPHISMS AND SUSCEPTIBILITY TO NONALCOHOLIC FATTY LIVER DISEASE.
Arquivos de gastroenterologia - 1 Jan 2000
Nobakht Hossein, Mahmoudi Touraj, Sabzikarian Mohammad, Tabaeian Seidamir Pasha, Rezamand Gholamreza, Asadi Asadollah, Farahani Hamid, Dabiri Reza, Mansour-Ghanaei Fariborz, Maleki Iradj, Zali Mohammad Reza
Abstract excerpt
BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is an increasing global health concern defined by excessive hepatic fat content in the absence of excessive alcohol consumption. OBJECTIVE: Given the pivotal role of insulin resistance in NAFLD, we hypothesized that insulin (INS) and insulin receptor (INSR) gene polymorphisms may be associated with NAFLD risk. METHODS: A total of 312 subjects, including 153...
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