Article
The G1057D polymorphism of insulin receptor substrate-2 associated with gestational diabetes mellitus.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Feb 2014
Ayaz Lokman, Karakaş Çelik Sevim, Cayan Filiz
Abstract excerpt
OBJECTIVE: The Gly1057D polymorphism in the insulin receptor substrate-2 (IRS-2) gene has been reported to be associated with insulin resistance, obesity and type 2 diabetes; little is known about its possible association with gestational diabetes mellitus (GDM). To investigate this association we determined the distribution of its genotypes and frequency of alleles in GDM patients. MATERIALS AND METHODS: The...
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