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Article

Causal effects of serum lipid biomarkers on early age-related macular degeneration using Mendelian randomization

21 Jul 2023

Abstract excerpt

Abstract Background Age-related macular degeneration (AMD) is one of the major causes of vision loss. Early AMD needs to be taken seriously, but the causal effects of lipid biomarkers on early AMD remain unclear. Methods In this study, two-sample Mendelian randomization (MR) analysis was performed to systematically assess the causal relationships between seven serum lipid biomarkers (apolipoprotein A (ApoA),...

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PMID: 37479984
DOI: 10.1186/s12263-023-00730-5

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