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Article

The causal effects of lifestyle, circulating, pigment, and metabolic factors on early age-related macular degeneration: a comprehensive Mendelian randomization study.

Journal of translational medicine - 1 Nov 2024

Shen Gang, Chen Yaqiong, Chen Jiahao, Wang Lingling, Cheng Huanhuan, Hu Bo, Gong Jiao

Abstract excerpt

PURPOSE: Early detection of lifestyle factors, skin and hair color, circulating parameters, and metabolic comorbidities is crucial for personalized prevention and treatment of early age-related macular degeneration (AMD). This study aimed to assess the relationships between genetically predicted comprehensive risk factors and early AMD. METHODS AND RESULTS: Publicly available genome-wide association study (GWAS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39482668
DOI: 10.1186/s12967-024-05773-9
PMCID: PMC11529295

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