Article
Role of plasma fatty acid in age-related macular degeneration: insights from a mendelian randomization analysis.
Lipids in health and disease - 29 Jun 2024
Han Guoge, Wei Pinghui, He Meiqin, Jia Lanbo, Su Qi, Yang Xiru, Hao Rui
Abstract excerpt
BACKGROUND: An imbalance in lipid metabolism has been linked to the development of AMD, but the causal relationship between AMD and plasma fatty acids (FAs) remains controversial. Using a two-sample Mendelian randomization (MR) approach, we sought to evaluate the impact of specific FA plasma levels on the risk of different AMD subtypes. METHODS: We analysed genome-wide association data of circulating FAs from...
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