Article
The tissue specificity of cancer genes
2025-09-21
Abstract excerpt
Defining genes that are somatically mutated in different cancers is a central goal of cancer genetics. Nevertheless, traditional definitions of “driver” genes based on pooled mutation frequency are biased toward common cancer types and tend to overlook genes that might be specific to rarer subtypes. As such, our understanding of the compendium of cancer genes is incomplete. In this study, we developed a statistica...
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Identifiers and source
- Literature Corpus work
- 8e08dbe0-1ac3-571a-904b-cb9c3e2467db
- DOI
- 10.1101/2025.09.21.677175