Article

Prioritizing context-specific genetic risk mechanisms in 11 solid cancers

2025-11-02

Abstract excerpt

<h4>Background</h4> While genome-wide association studies (GWAS) have identified hundreds of cancer-associated genetic variants, the specific biological contexts where these variants exert their effects remain largely unknown. We aimed to prioritize context-specific genetic risk mechanisms for 11 solid cancers at both genome-wide and single-variant resolutions. <h4>Methods</h4> We integrated cancer GWAS summary...

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Literature Corpus work: a8372530-b9a8-593d-b1a6-de58173a8557
DOI: 10.1101/2025.10.30.25339145

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