Article
Morphologic, immunophenotypic, molecular genetic, and clinical characterization in patients with SRSF2-mutated acute myeloid leukemia.
American journal of clinical pathology - 2 Nov 2023
Tatarian Joshua, Tupper Natalie, Li Peng, Feusier Julie, Abdo Maryam, Hyter Stephen, Gonzales Patrick R, Zhang Da, Woodroof Janet, Kelting Sarah, Godwin Andrew K, Cui Wei
Abstract excerpt
OBJECTIVES: SRSF2 mutations are known to be associated with poor outcomes in myelodysplastic neoplasm, but studies on their prognostic impact on acute myeloid leukemia (AML) remain limited. In this retrospective study, we analyzed clinical and pathologic characteristics of patients with AML and correlated the outcomes with SRSF2 mutations. METHODS: We characterized the morphologic, immunophenotypic, molecular,...
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