Article
Prognostic value of SRSF2 mutations in patients with de novo myelodysplastic syndromes: A meta-analysis.
PloS one - 1 Jan 2017
Zheng Xue, Zhan Zhi, Naren Duolan, Li Jing, Yan Tianyou, Gong Yuping
Abstract excerpt
BACKGROUND: The recent application of gene-sequencing technology has identified many new somatic mutations in patients with myelodysplastic syndromes (MDS). Among them, serine and arginine rich splicing factor 2 (SRSF2) mutations belonging to the RNA splicing pathway were of interest. Many studies have already reported the potential prognostic value of SRSF2 mutations in MDS patients, with controversial results....
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