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Article

Cellular specificity of androgen receptor, coregulators, and pioneer factors in prostate cancer

1 Sept 2022

Abstract excerpt

Androgen signalling, through the transcription factor androgen receptor (AR), is vital to all stages of prostate development and most prostate cancer progression. AR signalling controls differentiation, morphogenesis, and function of the prostate. It also drives proliferation and survival in prostate cancer cells as the tumour progresses; given this importance, it is the main therapeutic target for disseminated...

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PMID: 37435460
DOI: 10.1530/eo-22-0065

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