Article

Androgen receptor and prostate cancer

2016-01-01

Abstract excerpt

Androgens play a key role in the development and progression of prostate cancer, and androgen deprivation therapy (ADT) is the first line treatment for advanced disease. Although ADT is initially successful in controlling prostate cancer, many patients eventually become resistant to therapy and progress to develop lethal castration-resistant prostate cancer (CRPC). Androgens drive prostate cancer cell growth via t...

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Literature Corpus work: d8fa34e3-33f8-5655-8dee-5946293b26d4
DOI: 10.3934/molsci.2016.2.280

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