Establishment of a new reverse genetics system for respiratory syncytial virus under the control of RNA polymerase II

Abstract excerpt

A reverse genetics system for the respiratory syncytial virus (RSV), which causes acute respiratory illness, is an effective tool for understanding the pathogenicity of RSV. To date, a method dependent on T7 RNA polymerase is commonly used for RSV. Although this method is well established and recombinant RSV is well rescued from transfected cells, the requirement for artificial supply of T7 RNA polymerase limits...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Respiratory viral infections research
• Share to Viral gastroenteritis research and epidemiology
• Share to Viral Infections and Vectors