Article

First versatile reverse genetics system for feline coronavirus

2024-10-03

Abstract excerpt

Feline infectious peritonitis (FIP) is a fatal disease caused by feline coronavirus (FCoV). Although multiple gene mutations in FCoV likely account for FIP pathogenesis, molecular studies for FCoV have been limited due to the lack of a suitable reverse genetics system. In the present study, we established a rapid PCR-based system to generate recombinant FCoV using the circular polymerase extension reaction (CPER)...

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Literature Corpus work: 59b9380a-1e89-5b7a-8a48-6d8e0b8c6cef
DOI: 10.1101/2024.10.02.616382

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