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Genomic and evolutionary characteristics of metastatic gastric cancer by routes

8 Jul 2023

Abstract excerpt

BACKGROUND: In gastric cancer (GC) patients, metastatic progression through the lymphatic, hematogenous, peritoneal, and ovarian routes, is the ultimate cause of death. However, the genomic and evolutionary characteristics of metastatic GC have not been widely evaluated. METHODS: Whole-exome sequencing data were analyzed for 99 primary and paired metastatic gastric cancers from 15 patients who underwent...

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PMID: 37422528
DOI: 10.1038/s41416-023-02338-3

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