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Genomic alterations in gastric cancers discovered via whole-exome sequencing

1 Dec 2018

Abstract excerpt

BACKGROUND: Gastric cancer (GC) ranks the second in mortality rate among all cancers. Metastases account for most of the deaths in GC patients. Yet our understanding of GC and its metastasis mechanism is still very limited. METHODS: We performed 20 whole-exome sequencing (WES) on 5 typical metastatic gastric adenocarcinoma (GAC) patients with lymph node metastasis. We compared both the primary tumors to their...

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PMID: 30567531
DOI: 10.1186/s12885-018-5097-8

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