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Genome-wide association study of cardiometabolic multimorbidity in the UK Biobank.

Clinical genetics - 1 Jul 2024

Zhao Chenxuan, Ma Tianqi, Cheng Xunjie, Zhang Guogang, Bai Yongping

Abstract excerpt

Considering the high prevalence and poor prognosis of cardiometabolic multimorbidity (CMM), identifying causal factors and actively implementing preventive measures is crucial. However, Mendelian randomization (MR), a key method for identifying the causal factors of CMM, requires knowledge of the effects of SNPs on CMM, which remain unknown. We first analyzed the genetic overlap of single cardiometabolic diseases...

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Biological Specimen Banks
Cardiovascular Diseases
Genome-Wide Association Study
Mendelian Randomization Analysis
Multifactorial Inheritance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 38409652
DOI: 10.1111/cge.14513

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