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Article

The multivariate genetic architecture of psychiatric and insulin resistance multimorbidity.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2026

Mota Nina Roth, Fanelli Giuseppe, Erdogan Izel, Klein Marieke, Sprooten Emma, Fóthi Ábel, Ruisch I Hyun, Poelmans Geert, Alam Kazi Asraful, Haavik Jan, Wimberley Theresa, Arenella Martina, Barta Csaba, Jansen Willemijn J, Serretti Alessandro, Fabbri Chiara, Franke Barbara, Bralten Janita

Abstract excerpt

Psychiatric disorders frequently co-occur with insulin resistance (IR)-related conditions, including obesity, type 2 diabetes mellitus (T2DM), and metabolic syndrome (MetS). While genetic correlations have been reported, the genetics underlying this multimorbidity remains underexplored. Here, we investigate the joint genetic architecture of psychiatric-IR multimorbidity and explore links with the brain,...

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PMID: 42435748
DOI: 10.1016/j.euroneuro.2026.112906

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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