Article
Identification of Somatic Mutations in Plasma Cell-Free DNA from Patients with Metastatic Oral Squamous Cell Carcinoma.
International journal of molecular sciences - 20 Jun 2023
Lin Li-Han, Chang Kuo-Wei, Cheng Hui-Wen, Liu Chung-Ji
Abstract excerpt
The accurate diagnosis and treatment of oral squamous cell carcinoma (OSCC) requires an understanding of its genomic alterations. Liquid biopsies, especially cell-free DNA (cfDNA) analysis, are a minimally invasive technique used for genomic profiling. We conducted comprehensive whole-exome sequencing (WES) of 50 paired OSCC cell-free plasma with whole blood samples using multiple mutation calling pipelines and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
