Article
Cell-Free DNA as Biomarker in Oral Squamous Cell Carcinoma: Dynamics, Mutational Landscape and Clinical Implications.
Cells - 23 Mar 2026
Veiga Pedro, Barroso Leonor, Pires Luís Miguel, Mano Carolina, Caramelo Francisco, Carreira Isabel Marques, Ribeiro Ilda Patrícia, de Melo Joana Barbosa
Abstract excerpt
Oral squamous cell carcinoma (OSCC) is a prevalent form of head and neck cancer that typically develops on the lip or within the oral cavity. Although there have been advances in early detection and treatment, the prognosis for patients, particularly those with advanced-stage disease, remains poor. Liquid biopsy, particularly through the analysis of cell-free DNA (cfDNA) in plasma and urine, has emerged as a...
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