Article
Whole transcriptome sequencing identifies tumor-specific mutations in human oral squamous cell carcinoma.
BMC medical genomics - 4 Sept 2013
Zhang Qu, Zhang Jun, Jin Hong, Sheng Sitong
Abstract excerpt
BACKGROUND: The accumulation of somatic mutations in genes and molecular pathways is a major factor in the evolution of oral squamous cell carcinoma (OSCC), which sparks studies to identify somatic mutations with clinical potentials. Recently, massively parallel sequencing technique has started to revolutionize biomedical studies, due to the rapid increase in its throughput and drop in cost. Hence sequencing of...
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