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Article

Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities.

Theranostics - 1 Jan 2017

Su Shih-Chi, Lin Chiao-Wen, Liu Yu-Fan, Fan Wen-Lang, Chen Mu-Kuan, Yu Chun-Ping, Yang Wei-En, Su Chun-Wen, Chuang Chun-Yi, Li Wen-Hsiung, Chung Wen-Hung, Yang Shun-Fa

Abstract excerpt

Oral squamous cell carcinoma (OSCC), an epithelial malignancy affecting a variety of subsites in the oral cavity, is prevalent in Asia. The survival rate of OSCC patients has not improved over the past decades due to its heterogeneous etiology, genetic aberrations, and treatment outcomes. Improvement in therapeutic strategies and tailored treatment options is an unmet need. To unveil the mutational spectrum,...

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Topics

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28435450
DOI: 10.7150/thno.18551
PMCID: PMC5399578

Genes

CCND1
CASP8
CHUK
ELAVL1
EPHA2
FAT1
HRAS
NOTCH1
RASA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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