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Article

Somatic copy number alterations detected by ultra-deep targeted sequencing predict prognosis in oral cavity squamous cell carcinoma.

Oncotarget - 14 Aug 2015

Peng Chien-Hua, Liao Chun-Ta, Ng Ka-Pou, Tai An-Shun, Peng Shih-Chi, Yeh Jen-Pao, Chen Shu-Jen, Tsao Kuo-Chien, Yen Tzu-Chen, Hsieh Wen-Ping

Abstract excerpt

BACKGROUND: Ultra-deep targeted sequencing (UDT-Seq) has advanced our knowledge on the incidence and functional significance of somatic mutations. However, the utility of UDT-Seq in detecting copy number alterations (CNAs) remains unclear. With the goal of improving molecular prognostication and identifying new therapeutic targets, we designed this study to assess whether UDT-Seq may be useful for detecting CNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26087196
DOI: 10.18632/oncotarget.4336
PMCID: PMC4637328

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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