Comparing Genomic Landscapes of Oral and Cutaneous Squamous Cell Carcinoma of the Head and Neck: Quest for Novel Diagnostic Markers.

doi:10.1016/j.modpat.2023.100190

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Comparing Genomic Landscapes of Oral and Cutaneous Squamous Cell Carcinoma of the Head and Neck: Quest for Novel Diagnostic Markers.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Aug 2023

Gupta Ruta, Strbenac Dario, Satgunaseelan Laveniya, Cheung Veronica Ka-Yan, Narayanappa Harini, Ashford Bruce, Mitchell Jenny, Thind Amarinder, Palme Carsten E, Ch'ng Sydney, Low Tsu-Hui Hubert, Wykes James, Willet Cali E, Chew Tracy, Yang Jean, Ranson Marie, Clark Jonathan R

Abstract excerpt

Squamous cell carcinoma is the most common head and neck malignancy arising from the oral mucosa and the skin. The histologic and immunohistochemical features of oral squamous cell carcinoma (OSCC) and head and neck cutaneous squamous cell carcinoma (HNcSCC) are similar, making it difficult to identify the primary site in cases of metastases. With the advent of immunotherapy, reliable distinction of OSCC and...

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PMID: 37080394
DOI: 10.1016/j.modpat.2023.100190

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