Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma.

Scientific reports - 2 Aug 2023

Khan Naila, Khan Khushbukhat, Badshah Yasmin, Trembley Janeen H, Ashraf Naeem Mahmood, Shabbir Maria, Danish Lubna, Afsar Tayyaba, Almajwal Ali, Justin Saira, Hasan Zafarul, Razak Suhail

Abstract excerpt

Hepatocellular carcinoma is a leading cause of cancer-related deaths due to its complexity in diagnosis, chemo-resistance, and aggressive nature. Identifying pathogenic single nucleotide polymorphism (SNP) in protein kinase C iota (PKCι) can be a potential biomarker in the prognosis and treatment of HCC. This study investigated the association between a SNP in PRKCI and the Pakistani population's hepatocellular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Hepacivirus

Share to Hepatitis C

Share to Liver Neoplasms

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37532886
DOI: 10.1038/s41598-023-39804-0
PMCID: PMC10397245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating pathogenic SNP of PKCι in HCV-induced hepatocellular carcinoma.PMID 37532886Read ↗

Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma.Semantic proximity Read ↗

Non-synonymous SNPs variants of PRKCG and its association with oncogenes predispose to hepatocellular carcinomaSemantic proximity Read ↗

Association of CTLA-4 and IL-4 polymorphisms in viral induced liver cancer.Semantic proximity Read ↗

Computational insights into PKCθ non-synonymous SNPs: from structural changes to functional implications.Semantic proximity Read ↗

Comprehensive computational analysis of PKCδ non-synonymous variants identifies rs1703863535 as a potential breast cancer biomarker.Semantic proximity Read ↗

Assessment of exonic polymorphism of IDH2, KRAS1, TP53, and BRAF2 using PCR-RFLP in hepatocellular carcinoma: a case-control study from Arunachal Pradesh and Sikkim.Semantic proximity Read ↗

Influence of PRKCE non-synonymous variants on protein dynamics and functionality.Semantic proximity Read ↗

Deleterious single nucleotide polymorphisms of protein kinase R identified by the computational approach.Semantic proximity Read ↗

A multifaceted computational report on the variants effect on KIR2DL3 and IFNL3 candidate gene in HCV clearance.Semantic proximity Read ↗

Difference of polymorphism VEGF-gene rs699947 in Indonesian chronic liver disease population.Semantic proximity Read ↗

Polymorphism of the TLR4 gene reduces the risk of hepatitis C virus-induced hepatocellular carcinoma.Semantic proximity Read ↗

RNA protein kinase SNP at -226 C<T is a biomarker for the clearance of HCV among Egyptian patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.