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Article

Investigation of UTR Variants by Computational Approaches Reveal Their Functional Significance in PRKCI Gene Regulation.

Genes - 18 Jan 2023

Shah Hania, Khan Khushbukhat, Badshah Yasmin, Mahmood Ashraf Naeem, Shabbir Maria, Trembley Janeen H, Afsar Tayyaba, Abusharha Ali, Razak Suhail

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are associated with many diseases including neurological disorders, heart diseases, diabetes, and different types of cancers. In the context of cancer, the variations within non-coding regions, including UTRs, have gained utmost importance. In gene expression, translational regulation is as important as transcriptional regulation for the normal functioning of cells;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36833174
DOI: 10.3390/genes14020247
PMCID: PMC9956319

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