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Article

Elucidating the role of missense SNP of protein kinase C epsilon in HCV-induced hepatocellular carcinoma.

BMC cancer - 13 Feb 2023

Rehman Areeba, Shabbir Maria, Badshah Yasmin, Khan Khushbukhat, Trembley Janeen H, Ashraf Naeem Mahmood, Afsar Tayyaba, Almajwal Ali, Alruwaili Nawaf W, Alshamari Ali, Alanezi Tariq Nahar, Razak Suhail

Abstract excerpt

BACKGROUND: The protein kinase C (PKC) family of serine/threonine kinases contains more than ten isozymes that are involved in multiple signaling pathways, including cell cycle regulation and carcinogenesis. The PKCε isozyme is an oncogene known to be upregulated in various signaling pathways involved in hepatitis C virus (HCV)-induced hepatocellular carcinoma (HCC). However, there is no known association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36782184
DOI: 10.1186/s12885-023-10618-7
PMCID: PMC9926771

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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