Article
Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases.
Redox biology - 1 Aug 2023
Li Jingwen, Li Xinyue, Song Sijie, Sun Zhengwen, Li Yuanzhu, Yang Long, Xie Zhenhong, Cai Yikui, Zhao Yinping
Abstract excerpt
Cardiovascular diseases caused by atherosclerosis (AS) seriously endanger human health, which is closely related to vascular smooth muscle cell (VSMC) phenotypes. VSMC phenotypic transformation is marked by the alteration of phenotypic marker expression and cellular behaviour. Intriguingly, the mitochondrial metabolism and dynamics altered during VSMC phenotypic transformation. Firstly, this review combs VSMC...
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