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Article

Role and mechanisms of vascular smooth muscle cell phenotypic transition in diabetic macrovascular complications.

Biological research - 5 Jan 2026

Yao Qiyuan, Liu Hanyu, Wang Xueru, Zhang Zehua, Xie Hongyan, Xie Chunguang, Gao Hong

Abstract excerpt

Diabetic macrovascular complications, as one of the leading causes of mortality in diabetic patients, are characterized by insidious onset and high residual risk. Effective prevention and treatment of diabetic macrovascular injury remain critical clinical challenges, necessitating the development of novel therapeutic strategies targeting this complication. Although recent studies have demonstrated that vascular...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41491297
DOI: 10.1186/s40659-025-00665-8
PMCID: PMC12870442

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