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Article

Mutations in the S gene of hepatitis B virus in three generations of patients with chronic hepatitis B.

Virus genes - 1 Oct 2023

Naderi Malihe, Hosseini Seyed Masoud, Behnampour Naser, Shahramian Iraj, Moradi Abdolvahab

Abstract excerpt

Failure to neutralize HBsAg and subsequent escape from the host immune system may be caused by HBsAg mutations, particularly in the "a" determinant, which alters the antigenicity of the protein. The purpose of this study was to examine the frequency of S gene mutations in three generations of HBV cases in northeastern Iran. In this study, 90 patients with chronic HBV were assigned to three groups according to the...

Topics

Humans
Hepatitis B virus
Hepatitis B, Chronic
Hepatitis B Surface Antigens
Mutation
Hepatitis B Vaccines
Genotype
DNA, Viral
Hepatitis B

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37308753
DOI: 10.1007/s11262-023-02012-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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