Article
Hepatitis B caused by a hepatitis B surface antigen escape mutant.
Journal of gastroenterology - 1 Jan 2008
Kajiwara Eiji, Tanaka Yasuhito, Ohashi Tomoko, Uchimura Kotarou, Sadoshima Seizo, Kinjo Mitsuru, Mizokami Masashi
Abstract excerpt
Amino acid substitutions within the S gene involving the major antigenic a determinant of the hepatitis B virus (HBV) surface antigen (HBsAg) have been detected in cases of failure of immunization against the virus. Our report showed development of clinical hepatitis in presence of antibody to HBsAg in a healthy individual. A single amino acid substitution (G145R) within the a determinant of the HBsAg was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
