Article
Common and Distinct Genetic Architecture of Age at Diagnosis of Diabetes in South Indian and European Populations.
Diabetes care - 1 Aug 2023
Srinivasan Sundararajan, Liju Samuel, Sathish Natarajan, Siddiqui Moneeza K, Anjana Ranjit Mohan, Pearson Ewan R, Doney Alexander S F, Mohan Viswanathan, Radha Venkatesan, Palmer Colin N A
Abstract excerpt
OBJECTIVE: South Asians are diagnosed with type 2 diabetes (T2D) more than a decade earlier in life than seen in European populations. We hypothesized that studying the genomics of age of diagnosis in these populations may give insight into the earlier age diagnosis of T2D among individuals of South Asian descent. RESEARCH DESIGN AND METHODS: We conducted a meta-analysis of genome-wide association studies (GWAS)...
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