Article
Replication of genome-wide association signals in Asian Indians with early-onset type 2 diabetes.
Acta diabetologica - 1 Dec 2016
Chidambaram Manickam, Liju Samuel, Saboo Banshi, Sathyavani Kumpatla, Viswanathan Vijay, Pankratz Nathan, Gross Myron, Mohan Viswanathan, Radha Venkatesan
Abstract excerpt
AIMS: To evaluate the association of 87 genetic variants previously associated with type 2 diabetes mellitus (T2DM) in genome-wide association studies of populations of European ancestry in an Asian Indian population with early-onset type 2 diabetes mellitus (EOT2DM). METHODS: The study groups comprised of 877 type 2 diabetes individuals, 436 individuals with EOT2DM (age at diagnosis below 35 years), 441...
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