Article
Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?
Diabetologia - 1 Nov 2014
Sohani Zahra N, Deng Wei Q, Pare Guillaume, Meyre David, Gerstein Hertzel C, Anand Sonia S
Abstract excerpt
AIMS/HYPOTHESIS: South Asians are up to four times more likely to develop type 2 diabetes than white Europeans. It is postulated that the higher prevalence results from greater genetic risk. To evaluate this hypothesis, we: (1) systematically reviewed the literature for single nucleotide polymorphisms (SNPs) predisposing to type 2 diabetes in South Asians; (2) compared risk estimates, risk alleles and risk allele...
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