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Article

Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population.

Diabetes - 1 Sept 2018

Kwak Soo Heon, Chae Jeesoo, Lee Seungbok, Choi Sungkyoung, Koo Bo Kyung, Yoon Ji Won, Park Jin-Ho, Cho Belong, Moon Min Kyong, Lim Soo, Cho Young Min, Moon Sanghoon, Kim Young Jin, Han Sohee, Hwang Mi Yeong, Cho Yoon Shin, Lee Myung-Shik, Jang Hak C, Kang Hyun Min, Park Taesung, Cho Nam H, Kim Kyunga, Kim Jong-Il, Park Kyong Soo

Abstract excerpt

We investigated ethnicity-specific exonic variants of type 2 diabetes (T2D) and its related clinical phenotypes in an East Asian population. We performed whole-exome sequencing in 917 T2D case and control subjects, and the findings were validated by exome array genotyping in 3,026 participants. In silico replication was conducted for seven nonsynonymous variants in an additional 13,122 participants....

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Source

Identifiers

PMID: 29941447
DOI: 10.2337/db18-0361

Genes

PAX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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