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Article

CACNA1C genomewide supported psychosis genetic variation affects cortical brain white matter integrity in Chinese patients with schizophrenia.

The Journal of clinical psychiatry - 1 Nov 2014

Woon Puay San, Sum Min Yi, Kuswanto Carissa Nadia, Yang Guo Liang, Sitoh Yih Yian, Soong Tuck Wah, Lee Tih Shih, Nowinski Wieslaw Lucjan, Sim Kang

Abstract excerpt

OBJECTIVE: Recent genomewide association studies have implicated the calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C) genetic variant in schizophrenia, which is associated with functional brain changes and cognitive deficits in healthy individuals. However, the impact of CACNA1C on brain white matter integrity in schizophrenia remains unclear. On the basis of prior evidence of...

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Identifiers

PMID: 25470093
DOI: 10.4088/JCP.13m08777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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