Article
CDH1 and hereditary diffuse gastric cancer: a narrative review.
Chinese clinical oncology - 1 Jun 2023
Gregory Stephanie N, Davis Jeremy L
Abstract excerpt
BACKGROUND AND OBJECTIVE: Hereditary diffuse gastric cancer (HDGC) is an autosomal dominant cancer syndrome that increases lifetime risk of diffuse-type gastric cancer which carries a dismal overall survival. Due to the high prevalence of cancer in patients with CDH1 variants, early screening and...
Topics
- Humans
- Stomach Neoplasms
- Germ-Line Mutation
- Mutation
- Gastrectomy
- Adenocarcinoma
- Cadherins
- Genetic Predisposition to Disease
