Article
Riok1, A Novel Potential Target in MSI-High p53 Mutant Colorectal Cancer Cells.
Molecules (Basel, Switzerland) - 31 May 2023
Shechter Sharon, Ya'ar Bar Sapir, Khattib Hamdan, Gage Matthew J, Avni Dorit
Abstract excerpt
The vulnerabilities of cancer cells constitute a promising strategy for drug therapeutics. This paper integrates proteomics, bioinformatics, and cell genotype together with in vitro cell proliferation assays to identify key biological processes and potential novel kinases that could account, at least in part, for the clinical differences observed in colorectal cancer (CRC) patients. This study started by focusing...
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