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Article

Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival.

Cancer biology & medicine - 6 Jun 2023

Du Meizhi, Wang Yu, Vallis Jillian, Shariati Matin, Parfrey Patrick S, Mclaughlin John R, Wang Peizhong Peter, Zhu Yun

Abstract excerpt

OBJECTIVE: Leptin (LEP) is an obesity-associated adipokine associated with tumor cell growth. We examined the relevance of genetic variants of LEP and leptin receptor (LEPR) to colorectal cancer (CRC) survival by using data from the Newfoundland Familial Colorectal Cancer Study. METHODS: A total of 532 patients newly diagnosed with CRC between 1997 and 2003 were followed up until April 2010. Data on their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Leptin

Share to Regulation of Appetite and Obesity

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Identifiers

PMID: 37282602
DOI: 10.20892/j.issn.2095-3941.2022.0635
PMCID: PMC10291983

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