Article
Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk.
JAMA - 1 Oct 2008
Kaklamani Virginia G, Wisinski Kari B, Sadim Maureen, Gulden Cassandra, Do Albert, Offit Kenneth, Baron John A, Ahsan Habibul, Mantzoros Christos, Pasche Boris
Abstract excerpt
CONTEXT: Current epidemiological evidence suggests an association between obesity, hyperinsulinemia, and colorectal cancer risk. Adiponectin is a hormone secreted by the adipose tissue, and serum levels are inversely correlated with obesity and hyperinsulinemia. While there is evidence of an association between circulating adiponectin levels and colorectal cancer risk, no association between genes of the...
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