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Article

The leptin gene family and colorectal cancer: interaction with smoking behavior and family history of cancer.

PloS one - 1 Jan 2013

Liu Li, Zhong Rong, Wei Sheng, Xiang Hao, Chen Jigui, Xie Duoshuang, Yin Jieyun, Zou Li, Sun Jingwen, Chen Wei, Miao Xiaoping, Nie Shaofa

Abstract excerpt

BACKGROUND: Pathologic condition associated with metabolic syndrome traits seems to increase the risk of colorectal cancer. One mechanism underlying this relationship may involve the growth-promoting effects of the circulation hormones associated with obesity and insulin resistance, such as leptin. METHODOLOGY/PRINCIPAL FINDINGS: A two-stage case-control study was used to explore the role of polymorphisms of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23593308
DOI: 10.1371/journal.pone.0060777
PMCID: PMC3620466

Genes

LEPR
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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