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Article

Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma.

BMC cancer - 20 Feb 2006

Snoussi Kaouther, Strosberg A Donny, Bouaouina Noureddine, Ben Ahmed Slim, Helal A Noureddine, Chouchane Lotfi

Abstract excerpt

BACKGROUND: Leptin (LEP) has been consistently associated with angiogenesis and tumor growth. Leptin exerts its physiological action through its specific receptor (LEPR). We have investigated whether genetic variations in LEP and LEPR have implications for susceptibility to and prognosis in breast carcinoma. METHODS: We used the polymerase chain reaction and restriction enzyme digestion to characterize the...

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Source

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Identifiers

PMID: 16504019
DOI: 10.1186/1471-2407-6-38
PMCID: PMC1397853

Genes

LEP
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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